Living with Autoimmune Disorders: Why Awareness & Research Matter

Autoimmune disorders are among the most common yet least understood health conditions today. They occur when the immune system, designed to protect you, turns against your body. Instead of fighting off infections, it begins attacking healthy tissues, blood cells, or organs. More than 80 different autoimmune diseases exist, and each comes with unique symptoms and […]
October 28, 2025
Dr. Debra Weinstein
Dr. Debra Weinstein
Dr. Weinstein is a leading expert in decentralized clinical trials at Science 37, where she has been instrumental in advancing remote research opportunities since 2017. With active medical licensure in 46 states, she oversees a wide range of studies across diverse therapeutic areas, ensuring broader patient access to cutting-edge treatments.

A board-certified internist, Dr. Weinstein has over two decades of experience in clinical research. She has served as a principal investigator on more than 200 trials and has founded multiple research organizations specializing in internal medicine, rheumatology, orthopedics, and pain management. Recognized for her contributions to medical research, she has been named "Woman of the Year" by the National Association of Professional Women.

Autoimmune disorders are among the most common yet least understood health conditions today. They occur when the immune system, designed to protect you, turns against your body. Instead of fighting off infections, it begins attacking healthy tissues, blood cells, or organs. More than 80 different autoimmune diseases exist, and each comes with unique symptoms and challenges.

What Autoimmune Disorders Mean

The immune system protects your body from infection by identifying and fighting off viruses, bacteria, and toxins. With autoimmune disease, the immune system mistakenly attacks healthy tissues. The target could be the thyroid gland, the pancreas, the nervous system, or even blood cells.

Because the attack can happen in different organs, the symptoms are wide-ranging. Some people experience fatigue or muscle weakness, while others deal with digestive problems or skin rashes. Autoimmune disorders are chronic, which means they rarely go away. They require careful diagnosis and a long-term treatment plan.

A Closer Look at Common Conditions

Each autoimmune disorder looks different. Knowing the range helps you see why no single approach works for everyone.

  • Graves’ disease. This condition affects the thyroid gland. When your immune system disrupts thyroid function, it produces too much thyroid hormone. Symptoms may include rapid heartbeat, weight loss, anxiety, or heat intolerance. Genetic risk factors are essential because Graves' disease can run in families.
  • Multiple sclerosis (MS). In MS, the immune system damages the protective coating around nerve fibers. This disruption slows communication between the brain and the rest of the body. Muscle weakness, numbness, and balance issues are common. MS often follows a cycle of flares and recovery, but can also progress steadily.
  • Type 1 diabetes. With this condition, the immune system destroys insulin-producing cells in the pancreas. Without insulin, your body cannot control blood sugar levels. Daily insulin therapy and blood sugar monitoring are essential to prevent serious complications.
  • Systemic lupus erythematosus (lupus). Lupus is one of the most complex autoimmune disorders. It can affect joints, skin, kidneys, heart, and blood cells. Symptoms flare unpredictably, making lupus difficult to diagnose and manage.
  • Ulcerative colitis. This disorder affects the colon lining. Immune system attacks cause inflammation, abdominal pain, diarrhea, and rectal bleeding. People with ulcerative colitis often need ongoing medication, lifestyle changes, and close health care follow-up.
  • Celiac disease. In people with celiac disease, gluten triggers the immune system to attack the small intestine. This prevents the body from absorbing nutrients properly. Fatigue, anemia, and digestive distress are common, and the only effective treatment is a strict gluten-free diet.

Why Diagnosis Is Difficult

Woman getting her neck checked by doctor

Getting an accurate diagnosis for an autoimmune disorder is not always straightforward. Many early warning signs (fatigue, joint stiffness, digestive upset, skin rashes, or muscle weakness) also occur in other conditions. Because of this overlap, you may be treated for something else before doctors recognize the underlying autoimmune process.

Studies show that people with autoimmune disorders often wait years before receiving a correct diagnosis. This delay can allow symptoms to worsen and add stress that directly affects mental health outcomes. Living without answers can make flare-ups harder to manage and may leave you uncertain about the future.

Another challenge is that no single test confirms every autoimmune disease. A diagnosis usually requires a combination of blood tests, imaging studies, and physical exams. Doctors may look for antibodies that suggest the immune system attacks blood cells, the thyroid gland, or other tissues. Yet even when antibodies are present, the results do not always point to one clear condition.

Risk factors add another layer of complexity. Autoimmune disorders tend to run in families, but the inheritance pattern is not straightforward. You may carry specific genes that increase your risk, yet never develop disease. On the other hand, someone without a family history may still be diagnosed.

Why Awareness and Research Matter

Awareness does more than put a name to an illness. It helps you spot early warning signs, seek care sooner, and feel confident advocating for yourself in health care settings.

Autoimmune disorders often hide in plain sight because fatigue, joint pain, or digestive upset seem ordinary until they become chronic. When more people understand that these symptoms could signal autoimmune conditions, fewer patients are left searching for answers in silence. Awareness also opens the door to emotional support, something just as important as medical treatment when living with a chronic condition.

father and daughter visiting mother in hospital

Research is equally critical. Autoimmune disorders rarely follow a single pattern, which is why no one-size-fits-all treatment plan exists. Medical research is uncovering why these diseases often run in families, why women are more frequently affected, and how risk factors like infections or diet can trigger disease in someone already predisposed.

This knowledge is guiding the development of therapies that improve not only physical symptoms but also mental health outcomes, an area too often overlooked. For example, studies now explore how controlling inflammation in systemic lupus erythematosus may ease depression, or how stabilizing blood sugar in type 1 diabetes supports overall well-being.

Clinical trials make this progress possible. Unfortunately, traditional trials can be out of reach for many people. If you live with ulcerative colitis and experience unpredictable flare-ups, or if multiple sclerosis leaves you with mobility limitations, frequent clinic visits may feel impossible. Fatigue alone keeps many from participating. That is where decentralized clinical trials are changing the landscape.

Decentralized Clinical Trials at Science 37

Through organizations like Science 37, research can come directly to you. Virtual check-ins, at-home data collection, and medication delivery make participation realistic even if traveling to a hospital is difficult. This model not only gives more patients access to cutting-edge care, but also ensures autoimmune research reflects the diversity of real-world experiences, something essential if we want treatments that work for everyone.

If you live with Graves’ disease, lupus, celiac disease, type 1 diabetes, multiple sclerosis, or ulcerative colitis, consider exploring clinical trials with Science 37. Joining research is more than contributing data. It is helping build a future where autoimmune diseases are diagnosed faster, treated more effectively, and understood more fully.

hello world!

Read More

Woman warming up and stretching before exercise
November Health Awareness Calendar: What This Month Means for Research & Prevention
November marks several important health observances in the United States. The Department of Health and Human Services and related health organizations use this month to raise awareness about chronic health conditions and support public education. The November Health awareness calendar marks: These observances highlight a specific health challenge and they each encourage us to focus […]
Read More
Doctor giving advice to elderly woman
Living with Autoimmune Disorders: Why Awareness & Research Matter
Autoimmune disorders are among the most common yet least understood health conditions today. They occur when the immune system, designed to protect you, turns against your body. Instead of fighting off infections, it begins attacking healthy tissues, blood cells, or organs. More than 80 different autoimmune diseases exist, and each comes with unique symptoms and […]
Read More
Young woman sleeping in classroom
Living with Narcolepsy or Idiopathic Hypersomnia: Symptoms and Support
If you always feel tired, even after what seems like a full night’s rest, you may wonder if something more than ordinary sleepiness is happening. For some people, the explanation lies in conditions such as narcolepsy or idiopathic hypersomnia. These neurological sleep disorders affect how your nervous system regulates sleep and wakefulness. According to the […]
Read More
1 2 3 25
© 2025 Science 37 | All Rights Reserved